Itraconazole is a broad-spectrum triazole antifungal medication used to treat various fungal infections, including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis of fingernails and toenails. It works by inhibiting ergosterol synthesis in fungal cell membranes, disrupting their integrity and halting growth, with an active metabolite hydroxyitraconazole enhancing its potency. Available in oral capsules, tablets, and solution forms like Sporanox or Tolsura, it effectively manages systemic infections in both immunocompromised and non-immunocompromised patients, such as those with HIV or post-transplant conditions, as well as superficial mycoses and yeast infections of the mouth, throat, or esophagus.